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A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression.

Major depression is a common and severe psychiatric disorder with a highly polygenic genetic architecture. Genome-wide association studies have successfully identified multiple independent genetic loci that harbour variants associated with major depression, but the exact causal genes and biological...

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Библиографические подробности
Главные авторы: Zachary F Gerring, Eric R Gamazon, Eske M Derks, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2019-07-01
Серии:PLoS Genetics
Online-ссылка:https://doi.org/10.1371/journal.pgen.1008245
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