Deletion of the CYP2D6 gene as a likely explanation for the serious side effects of the antipsychotic drug pimozide: a case report

CYP2D6 analysis prior to the prescription of pimozide is required above a certain dose by the Food and Drug Administration in order to detect individuals with the poor metabolizer status. This precautionary measure aims to prevent the occurrence of serious adverse drug reactions. This study presents...

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Bibliografische Detailangaben

Hauptverfasser:	Fernando Facal, Begoña Portela, Almudena Gil-Rodríguez, Francisco Barros, Olalla Maroñas, Angel Carracedo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-08-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	severe adverse reactions pharmacogenetics parkinsonism extrapyramidal syndrome risperidone pimozide
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1237446/full
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