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Clinical and laboratory markers to distinguish VEXAS from Schnitzler's syndrome: data from the AIDA network registries

BackgroundA substantial overlap in demographic, clinical, and laboratory features can complicate the differential diagnosis between Schnitzler's syndrome and VEXAS syndrome. The present study was undertaken to identify clinical and laboratory parameters that should raise suspicion for VEXAS syndrome...

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Автори: Valeria Caggiano, Jessica Sbalchiero, Micol Frassi, Eduardo Martín-Nares, Andrea Hinojosa-Azaola, Mariusz Sikora, Karina Jahnz-Różyk, Francesca Crisafulli, Franco Franceschini, Paolo Airò, Guillermo Arturo Guaracha-Basañez, Jiram Torres-Ruiz, Paolo Sfriso, Sara Bindoli, Chiara Baggio, José Hernández-Rodríguez, Verónica Gómez Caverzaschi, Gerard Espinosa, Henrique A. Mayrink Giardini, Rafael Alves Cordeiro, Andrés González-García, Mercedes Peña Rodríguez, Giuseppe Lopalco, Florenzo Iannone, Ombretta Viapiana, Abdurrahman Tufan, Hamit Kucuk, Pravin Hissaria, Mark Beecher, Amato De Paulis, Ilaria Mormile, Lorenzo Dagna, Corrado Campochiaro, Antonio Gidaro, Leyla La Cava, Serena Bugatti, Alessandra Milanesi, Guillermo Ruiz-Irastorza, Matteo Piga, Fabrizio Conti, Paolo Moscato, Daniela Opris-Belinski, Rosetta Vitetta, Cecilia Chighizola, Andreas Recke, Fernando Tornero-Romero, Marcella Prete, Marcello Govoni, Giacomo Emmi, Perla Ayumi Kawakami-Campos, Paola Triggianese, Carmelo Gurnari, Gaafar Ragab, Alberto Balistreri, Marcin Ziȩtkiewicz, Ewa Wiesik-Szewczyk, Bruno Frediani, Claudia Fabiani, Anna Sicuranza, Monica Bocchia, Luca Cantarini, Antonio Vitale
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2026-01-01
Серія:Frontiers in Medicine
Предмети:
UBA1 mutation
autoinflammatory diseases
cutaneous manifestations
differential diagnosis
treatment
Онлайн доступ:https://www.frontiersin.org/articles/10.3389/fmed.2025.1659758/full
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