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LTBR acts as a novel immune checkpoint of tumor‐associated macrophages for cancer immunotherapy

Abstract Tumor‐associated macrophages (TAMs) greatly contribute to immune checkpoint inhibitor (ICI) resistance of cancer. However, its underlying mechanisms and whether TAMs can be promising targets to overcome ICI resistance remain to be unveiled. Through integrative analysis of immune multiomics...

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Главные авторы: Liang Wang, Jieyi Fan, Sifan Wu, Shilin Cheng, Junlong Zhao, Fan Fan, Chunchen Gao, Rong Qiao, Qiqi Sheng, Yiyang Hu, Yong Zhang, Pengjun Liu, Zhe Jiao, Tiaoxia Wei, Jie Lei, Yan Chen, Hongyan Qin
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley 2024-10-01
Серии:iMeta
Предметы:
immune checkpoint
LTBR
myeloid derived suppressor cells
CD8+ T cells
tumor‐associated macrophages
Online-ссылка:https://doi.org/10.1002/imt2.233
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