Tailoring Corynebacterium glutamicum towards increased malonyl-CoA availability for efficient synthesis of the plant pentaketide noreugenin

Abstract Background In the last years, different biotechnologically relevant microorganisms have been engineered for the synthesis of plant polyphenols such as flavonoids and stilbenes. However, low intracellular availability of malonyl-CoA as essential precursor for most plant polyphenols of intere...

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Auteurs principaux:	Lars Milke, Nicolai Kallscheuer, Jannick Kappelmann, Jan Marienhagen
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2019-04-01
Collection:	Microbial Cell Factories
Sujets:	Malonyl-CoA Corynebacterium glutamicum Noreugenin Metabolic engineering Acetyl-CoA carboxylase
Accès en ligne:	http://link.springer.com/article/10.1186/s12934-019-1117-x
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