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Potency assays and biomarkers for cell-based advanced therapy medicinal products

Advanced Therapy Medicinal Products (ATMPs) based on somatic cells expanded in vitro, with or without genetic modification, is a rapidly growing area of drug development, even more so following the marketing approval of several such products. ATMPs are produced according to Good Manufacturing Practi...

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Principais autores: Chiara Capelli, Carolina Cuofano, Chiara Pavoni, Simona Frigerio, Daniela Lisini, Sara Nava, Michele Quaroni, Valentina Colombo, Francesco Galli, Svetlana Bezukladova, Paola Panina-Bordignon, Giuseppe Gaipa, Patrizia Comoli, Giulio Cossu, Gianvito Martino, Andrea Biondi, Martino Introna, Josée Golay
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-06-01
Serier:Frontiers in Immunology
Fag:
advanced therapy medicinal product (ATMP)
potency
CAR (chimeric antigen receptor)
T cell therapy
stem cell
tissue regeneration
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1186224/full
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