Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease.

Ankylosing spondylitis (AS) is a common inflammatory arthritic condition. Overt inflammatory bowel disease (IBD) occurs in about 10% of AS patients, and in addition 70% of AS cases may have subclinical terminal ileitis. Spondyloarthritis is also common in IBD patients. We therefore tested Crohn'...

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Main Authors: Patrick Danoy, Karena Pryce, Johanna Hadler, Linda A Bradbury, Claire Farrar, Jennifer Pointon, Australo-Anglo-American Spondyloarthritis Consortium, Michael Ward, Michael Weisman, John D Reveille, B Paul Wordsworth, Millicent A Stone, Spondyloarthritis Research Consortium of Canada, Walter P Maksymowych, Proton Rahman, Dafna Gladman, Robert D Inman, Matthew A Brown
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2010-12-01
Serier:PLoS Genetics
Online adgang:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001195&type=printable
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