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Bioinspired cascade nanozymes reprogram osteoarthritic joints: Mn-Nb2C-CeO2 mediated immuno-redox circuitry for self-healing cartilage

Osteoarthritis (OA), a debilitating joint disorder affecting millions worldwide, is characterized by persistent inflammation, oxidative stress, and irreversible cartilage breakdown, yet remains without disease-modifying therapies. Inspired by natural enzymatic cascades, we developed a bioinspired na...

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Principais autores: Yan Ma, Yufei Liu, Pan Chen, Yingfeng Su, Zizheng Chen, Xiangqian Fang, Yujun Zhang, Junxin Chen, Wenbin Xu
Format: Artigo
Sprog:Inglês
Udgivet: Tsinghua University Press 2026-01-01
Serier:Nano Research
Fag:
bioinspired nanozymes
nitrogen doping
osteoarthritis
immuno-redox circuitry
cartilage reprogramming
mxene hydrogels
Online adgang:https://www.sciopen.com/article/10.26599/NR.2025.94908293
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