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A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

ABSTRACT In solid organ transplantation, monocytes and macrophages play a cross‐cutting role in the rejection process, irrespective of the transplanted tissue and the type of rejection. Here, we integrated multiple single‐cell assays (>150,000 cells) with a broad spectrum of blood‐derived and renal...

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Principais autores: Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-02-01
Serier:Advanced Science
Fag:
allorecognition
kidney transplant rejection
monocytes differentiation
Online adgang:https://doi.org/10.1002/advs.202521294
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