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Crystal structure of a lipin/Pah phosphatidic acid phosphatase

Lipin/Pah phosphatidic acid phosphatases generate diacylglycerol to regulate triglyceride synthesis and cellular signaling. Here authors determine structures of Tetrahymena thermophila Pah2 and identify an N-terminal amphipathic helix essential for membrane association.

Furkejuvvon:
Bibliográfalaš dieđut
Váldodahkkit: Valerie I. Khayyo, Reece M. Hoffmann, Huan Wang, Justin A. Bell, John E. Burke, Karen Reue, Michael V. Airola
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2020-03-01
Ráidu:Nature Communications
Liŋkkat:https://doi.org/10.1038/s41467-020-15124-z
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