Heme oxygenase-1 is an equid alphaherpesvirus 8 replication restriction host protein and suppresses viral replication via the PKCβ/ERK1/ERK2 and NO/cGMP/PKG pathway

ABSTRACTEquid alphaherpesvirus 8 (EqHV-8) is one of the most economically important viruses that is known to cause severe respiratory disease, abortion, and neurological syndromes in equines. However, no effective vaccines or therapeutic agents are available to control EqHV-8 infection. Heme oxygena...

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Hlavní autoři:	Tongtong Wang, Shuwen Li, Xinyao Hu, Yiqing Geng, Li Chen, Wenqiang Liu, Juan Zhao, Wenxia Tian, Changfa Wang, Yubao Li, Liangliang Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2024-04-01
Edice:	Microbiology Spectrum
Témata:	EqHV-8 HO-1 biliverdin anti-viral effect mouse model
On-line přístup:	https://journals.asm.org/doi/10.1128/spectrum.03220-23
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