Effects of catechol-O-methyltransferase enzyme Val158Met polymorphism on cognitive functions in schizophrenic patients

Objective: Catechol-O-Methyltransferase (COMT) enzyme plays an important role in dopamine metabolism. Three different genotypes have been defined, one resulting from a valine (val)→methionine (met) amino acid change due to a guanine→adenine nucleotide change at codon 108/158 of the COMT gene, while...

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Hlavní autoři:	Gulfizar Sozeri Varma, Filiz Karadag, M. Emin Erdal, Özlem İzci Ay, Neslihan Levent, Çiğdem Tekkanat, Tuba Edgünlü Gökdoğan, Hasan Herken
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Mesut Çetin 2021-02-01
Edice:	Psychiatry and Clinical Psychopharmacology
Témata:	Schizophrenia catechol-O-methyltransferase (COMT) Val158Met polymorphism executive function attention memory
On-line přístup:	https://psychiatry-psychopharmacology.com/index.php/pub/article/view/689
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