Angiopep-2 functionalized poly(lactic-co-glycolic acid) nanocomposite for synergistic chemo-immunotherapy in glioma through STING pathway activation

Effective treatment of glioma remains challenging due to the limited permeability of the blood–brain barrier (BBB) and the highly immunosuppressive tumor microenvironment. To address these obstacles, we develop a multifunctional nanocomposite, Ang-PMT, that enables synergistic chemo-immunotherapy by...

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Autori principali:	Guangrong Zheng, Tengfei Ke, Hong Huang, Yue Zhang, Jincui Chen, Zhiqiang Ouyang, Shasha Bao, Guanghai Fei, Haiyan Yang, Chengde Liao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2026-03-01
Serie:	Materials & Design
Soggetti:	Glioma Tumor immune microenvironment STING pathway Targeted drug delivery Magnetic resonance imaging
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0264127526002224
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