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Single-Cell RNA-Seq Analysis Links DNMT3B and PFKFB4 Transcriptional Profiles with Metastatic Traits in Hepatoblastoma

Hepatoblastoma is the most common primary liver cancer in children. Poor outcomes are primarily associated with patients who have distant metastases. Using the Mammalian Metabolic Enzyme Database, we investigated the overexpression of metabolic enzymes in hepatoblastoma tumors compared to noncancero...

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Principais autores: Christophe Desterke, Raquel Francés, Claudia Monge, Agnès Marchio, Pascal Pineau, Jorge Mata-Garrido
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-10-01
Serier:Biomolecules
Fag:
hepatoblastoma
metastasis
CHIC risk
metabolism
epigenetics
DNA methylation
Online adgang:https://www.mdpi.com/2218-273X/14/11/1394
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