Efficacy Differences of First-line EGFR-TKIs Alone vs in Combination with Chemotherapy in Advanced Lung Adenocarcinoma Patients with Sensitive EGFR Mutation and Concomitant Non-EGFR Genetic Alterations

Background and objective: Epidermal growth factor receptor (EGFR) mutations are often associated with non-EGFR genetic alterations, which may be a reason for the poor efficacy of EGFR tyrosine kinase inhibitors (TKIs). Here we conducted this study to explore whether EGFR-TKIs combined with chemother...

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Huvudupphov:	Guowei ZHANG, Ruirui CHENG, Yuanyuan NIU, Huijuan WANG, Xiangtao YAN, Mina ZHANG, Xiaojuan ZHANG, Jinpo YANG, Chunhua WEI, Zhiyong MA
Materialtyp:	Artigo
Språk:	Chinês
Utgiven:	Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2022-09-01
Serie:	Chinese Journal of Lung Cancer
Ämnen:	lung neoplasms egfr mutation concomitant genetic alteration targeted therapy chemotherapy
Länkar:	http://dx.doi.org/10.3779/j.issn.1009-3419.2022.102.34
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Efficacy Differences of First-line EGFR-TKIs Alone vs in Combination with Chemotherapy in Advanced Lung Adenocarcinoma Patients with Sensitive EGFR Mutation and Concomitant Non-EGFR Genetic Alterations

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