Endoplasmic reticulum stress related genome-wide Mendelian randomization identifies therapeutic genes for ulcerative colitis and Crohn’s disease

Background: Endoplasmic reticulum stress (ERS) is an important pathophysiological mechanism in ulcerative colitis (UC) and Crohn’s disease (CD). ERS-related genes may be influenced by genetic factors and intestinal inflammation. However, the role of ERS as a trigger or potential etiological factor f...

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Principais autores:	Menglong Zou, Qiaoli Liang, Wei Zhang, Ying Zhu, Yin Xu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-10-01
coleção:	Frontiers in Genetics
Assuntos:	summary data-based Mendelian randomization endoplasmic reticulum stress ulcerative colitis Crohn’s disease integrative omics analysis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1270085/full
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