Transcriptomic profiling of cumulus cells reveals dysregulated genes and pathways in PCOS-related infertility

Abstract Background Polycystic ovarian syndrome (PCOS) is a leading cause of infertility and metabolic dysfunction in women, characterized by hyperandrogenism, anovulation, and insulin resistance. Cumulus cells play a crucial role in folliculogenesis and oocyte maturation, necessitating a deeper und...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Akeem Babatunde Sikiru, Nurulfiza Mat Isa, Kasim Sakran Abass, Muibat Adesola Adeniran, Stephen Sunday Acheneje Egena, Karimot Akinola
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: SpringerOpen 2025-08-01
Saila:Middle East Fertility Society Journal
Gaiak:
PCOS
Cumulus cells
GNAT1
Oocyte competence, Infertility
Sarrera elektronikoa:https://doi.org/10.1186/s43043-025-00241-w
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