Effects of the selective chymase inhibitor TEI‐F00806 on the intrarenal renin–angiotensin system in salt‐treated angiotensin I‐infused hypertensive mice

New Findings What is the central question of this study? Can chymase inhibition prevent angiotensin I‐induced hypertension through inhibiting the conversion of angiotensin I to angiotensin II in the kidney? What is the main finding and its importance? Treatment with TEI‐F00806 decreased angiotensin...

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Autores principales:	Tuba M. Ansary, Maki Urushihara, Yoshihide Fujisawa, Sayaka Nagata, Hidenori Urata, Daisuke Nakano, Hitomi Hirofumi, Kazuo Kitamura, Shoji Kagami, Akira Nishiyama
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2018-11-01
Colección:	Experimental Physiology
Materias:	blood pressure chymase high salt intrarenal RAS
Acceso en línea:	https://doi.org/10.1113/EP087209
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