A nonhuman primate model with Alzheimer’s disease-like pathology induced by hippocampal overexpression of human tau

Abstract Background Alzheimer’s disease (AD) is one of the most burdening diseases of the century with no disease-modifying treatment at this time. Nonhuman primates (NHPs) share genetic, anatomical, and physiological similarities with humans, making them ideal model animals for investigating the pa...

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मुख्य लेखकों:	Zhouquan Jiang, Jing Wang, Yongpeng Qin, Shanggong Liu, Bin Luo, Fan Bai, Huiyi Wei, Shaojuan Zhang, Junjie Wei, Guoyu Ding, Long Ma, Shu He, Rongjie Chen, Ying Sun, Yi Chen, Lu Wang, Hao Xu, Xiangyu Wang, Gong Chen, Wenliang Lei
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	BMC 2024-01-01
श्रृंखला:	Alzheimer’s Research & Therapy
विषय:	Alzheimer’s disease Human tau 3R tau 4R tau Tau hyperphosphorylation Nonhuman primate
ऑनलाइन पहुंच:	https://doi.org/10.1186/s13195-024-01392-0
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