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Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections.

Bacterial invasion of synovial joints, as in infectious or septic arthritis, can be difficult to treat in both veterinary and human clinical practice. Biofilms, in the form of free-floating clumps or aggregates, are involved with the pathogenesis of infectious arthritis and periprosthetic joint infe...

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Autori principali: Jessica M Gilbertie, Lauren V Schnabel, Noreen J Hickok, Megan E Jacob, Brian P Conlon, Irving M Shapiro, Javad Parvizi, Thomas P Schaer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2019-01-01
Serie:PLoS ONE
Accesso online:https://doi.org/10.1371/journal.pone.0221012
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