The transcription factor Blimp-1 is suppressed by SLAMF1 and drives Treg cell-mediated immune evasion in non-small cell lung cancer

Abstract Background Immune checkpoint inhibitors targeting the interaction between PD1 and PDL1 are effective for immunotherapy in non-small cell lung cancer (NSCLC). However, only subgroups of patients respond to therapy, suggesting the existence of resistance mechanisms. Methods In this study, we...

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Bibliografiske detaljer

Principais autores:	Susetta Finotto, Denis I. Trufa, Sonja Trump, Laura Neurath, Katja Hohenberger, Patrick Tausche, Nicole Neurath, Sviatoslav Tsiumpala, Susanne Mittler, Andreas Wild, Elvedina Nendel, Horia Sirbu, Arndt Hartmann
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2025-10-01
Serier:	BJC Reports
Online adgang:	https://doi.org/10.1038/s44276-025-00184-9
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