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Released Myeloperoxidase Attenuates Neutrophil Migration and Accumulation in Inflamed Tissue

Neutrophil (PMN) recruitment to sites of insult is critical for host defense, however excessive PMN activity and tissue accumulation can lead to exacerbated inflammation and injury. Myeloperoxidase (MPO) is a PMN azurophilic granule enzyme, which together with H2O2, forms a powerful antimicrobial sy...

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Hlavní autoři: Jacob F. Rehring, Triet M. Bui, Carlos Samuel Galán-Enríquez, Jessica M. Urbanczyk, Xingsheng Ren, Hannah L. Wiesolek, David P. Sullivan, Ronen Sumagin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-04-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2021.654259/full
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