Improving the Efficacy of Antimicrobials against Biofilm-Embedded Bacteria Using Bovine Hyaluronidase Azoximer (Longidaza^®)

While in a biofilm, bacteria are extremely resistant to both antimicrobials and the immune system, leading to the development of chronic infection. Here, we show that bovine hyaluronidase fused with a copolymer of 1,4-ethylenepiperazine N-oxide and (N-carboxymethyl) -1,4-ethylenepiperazinium bromide...

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Bibliografiska uppgifter

Huvudupphov:	Elena Trizna, Diana Baidamshina, Anna Gorshkova, Valentin Drucker, Mikhail Bogachev, Anton Tikhonov, Airat Kayumov
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2021-10-01
Serie:	Pharmaceutics
Ämnen:	bacterial biofilms enzymatic destruction of the biofilm bovine hyaluronidase azoximer (Longidaza)
Länkar:	https://www.mdpi.com/1999-4923/13/11/1740
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