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Long-term analysis of humoral responses and spike-specific T cell memory to Omicron variants after different COVID-19 vaccine regimens

BackgroundThe emergence of SARS-CoV-2 variants has raised concerns about the sustainability of vaccine-induced immunity. Little is known about the long-term humoral responses and spike-specific T cell memory to Omicron variants, with specific attention to BA.4/5, BQ.1.1, and XBB.1.MethodsWe assessed...

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Gardado en:
Principais autores: Chia-Lo Ho, Li-Chen Yen, Hong-Wei Huang, Chun-Chi Lu, Yi-Jen Hung, Ching-Len Liao, Chin-Mao Hung, Kuo-Chou Chiu
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Assuntos:
SARS-CoV-2
Omicron variant
vaccination
neutralizing antibody
cellular immune response
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1340645/full
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