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Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias. Venet...

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Principais autores: Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2025-03-01
coleção:CPT: Pharmacometrics & Systems Pharmacology
Acesso em linha:https://doi.org/10.1002/psp4.13284
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