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Low prevalence of CHEK2 gene mutations in multiethnic cohorts of breast cancer patients in Malaysia.

CHEK2 is a protein kinase that is involved in cell-cycle checkpoint control after DNA damage. Germline mutations in CHEK2 gene have been associated with increase in breast cancer risk. The aim of this study is to identify the CHEK2 gene germline mutations among high-risk breast cancer patients and i...

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Autors principals: Suriati Mohamad, Nurismah Md Isa, Rohaizak Muhammad, Nor Aina Emran, Nor Mayah Kitan, Peter Kang, In Nee Kang, Nur Aishah Mohd Taib, Soo Hwang Teo, Sharifah Noor Akmal
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-01-01
Col·lecció:PLoS ONE
Accés en línia:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117104&type=printable
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