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Crocin and eugenol enhance radiosensitivity in oral squamous cell carcinoma cells via apoptotic pathways and cell cycle regulation. Type of study: in vitro

Abstract Background Oral squamous cell carcinoma (OSCC) continues to be a significant clinical challenge because of radioresistance and treatment-related toxicities. Safer radiosensitizers are urgently needed. Objective This study assessed the radiosensitizing effects of crocin and eugenol on OSCC-1...

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Principais autores: Mohammad Taha Heidari, Mahdi Fasihi-Ramandi, Samira Hajisadeghi, Elham Keykha
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-01-01
coleção:BMC Complementary Medicine and Therapies
Assuntos:
Oral squamous cell carcinoma (OSCC)
Crocin
Eugenol
Radiosensitizer
Natural compounds
Alternative therapies
Acesso em linha:https://doi.org/10.1186/s12906-026-05261-1
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