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A GBP 130 derived peptide from Plasmodium falciparum binds to human erythrocytes and inhibits merozoite invasion in vitro

The malarial GBP 130 protein binds weakly to intact human erythrocytes; the binding sites seem to be located in the repeat region and this region's antibodies block the merozoite invasion. A peptide from this region (residues from 701 to 720) which binds to human erythrocytes was identified. This pe...

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Principais autores: Jorge E Suarez, Mauricio Urquiza, Hernando Curtidor, Luis E Rodriguez, Marisol Ocampo, Elizabeth Torres, Fanny Guzman, Manuel Elkin Patarroyo
Format: Artigo
Sprog:Inglês
Udgivet: Fundação Oswaldo Cruz (FIOCRUZ) 2000-08-01
Serier:Memorias do Instituto Oswaldo Cruz
Fag:
Plasmodium falciparum
GBP 130
binding assay
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000400009
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