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Intravenous Reelin rescues despair-like behavior, Reelin cells in the dentate sub-granular zone, and spleen atrophy in the cyclic corticosterone model of recurring depressive episodes

Novel antidepressants are predominantly evaluated preclinically in rodent models of chronic stress in which animals experience a single prolonged exposure to chronic stress prior to treatment. Rodent models of a single episode of chronic stress translate poorly to human depressive disorders, which a...

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Váldodahkkit: B. S. Reive, J. Johnston, C. L. Sánchez-Lafuente, Kaylene Scheil, K. Kurz, L. E. Kalynchuk, H. J. Caruncho
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2024-02-01
Ráidu:Frontiers in Pharmacology
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fphar.2024.1368620/full
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