Anabolic effects of IGF-1 signaling on the skeleton
This review focuses on the anabolic effects of IGF-1 signaling on the skeleton, emphasizing the requirement for IGF-1 signaling in normal bone formation and remodeling. We first discuss the genomic context, splicing variants and species conservation of the IGF-1 locus. The modulation of IGF-1 action...
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| Principais autores: | , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Frontiers Media S.A.
2013-02-01
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| 丛编: | Frontiers in Endocrinology |
| 主题: | |
| 在线阅读: | http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00006/full |
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