Glial Activation, Neuroinflammation, and Loss of Neuroprotection in Chronic Pain: Cellular Mechanisms and Emerging Therapeutic Strategies

Chronic pain is increasingly regarded as a condition of glia–neuronal dysregulation driven by persistent neuroinflammatory signaling. Following injury to nerves or tissues, glial cells, including astrocytes or satellite glial cells, undergo changes in their phenotype, thereby amplifying painful stim...

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Autores principales:	Alyssa McKenzie, Rachel Dombrower, Nitchanan Theeraphapphong, Sophia McKenzie, Munther A. Hijazin
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2025-12-01
Colección:	Biomedicines
Materias:	microglia astrocytes satellite glial cells glial activation neuroinflammation neuroprotection
Acceso en línea:	https://www.mdpi.com/2227-9059/14/1/58
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