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Exploiting next-generation sequencing in antibody selections – a simple PCR method to recover binders

Antibody discovery using invitro display technologies such as phage and/or yeast display has become acornerstone in many research and development projects, including the creation of new drugs for clinical use. Traditionally, after the selection phase, random clones are isolated for binding validatio...

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Autori principali: Fortunato Ferrara, Andre A. Teixeira, Leslie Naranjo, M. Frank Erasmus, Sara D’Angelo, Andrew R.M. Bradbury
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2020-01-01
Serie:mAbs
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Accesso online:https://www.tandfonline.com/doi/10.1080/19420862.2019.1701792
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