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Impact of Oncogenic Changes in p53 and KRAS on Macropinocytosis and Ferroptosis in Colon Cancer Cells and Anticancer Efficacy of Niclosamide with Differential Effects on These Two Processes

Mutations in p53 and KRAS are seen in most cases of colon cancer. The impact of these mutations on signaling pathways related to cancer growth has been studied in depth, but relatively less is known on their effects on amino acid transporters in cancer cells. This represents a significant knowledge...

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Autors principals: Nhi T. Nguyen, Souad R. Sennoune, Gunadharini Dharmalingam-Nandagopal, Sathish Sivaprakasam, Yangzom D. Bhutia, Vadivel Ganapathy
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2024-05-01
Col·lecció:Cells
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Accés en línia:https://www.mdpi.com/2073-4409/13/11/951
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