Peripheralization Strategies Applied to Morphinans and Implications for Improved Treatment of Pain

Opioids are considered the most effective analgesics for the treatment of moderate to severe acute and chronic pain. However, the inadequate benefit/risk ratio of currently available opioids, together with the current ‘opioid crisis’, warrant consideration on new opioid analgesic discovery strategie...

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Detalhes bibliográficos

Principais autores:	Helmut Schmidhammer, Mahmoud Al-Khrasani, Susanna Fürst, Mariana Spetea
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-06-01
coleção:	Molecules
Assuntos:	pain analgesia opioid receptors peripheral analgesia peripherally restricted opioids morphine
Acesso em linha:	https://www.mdpi.com/1420-3049/28/12/4761
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