Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants

Abstract Tau aggregation is a hallmark feature in a subset of patients with frontotemporal dementia (FTD). Early and selective loss of von Economo neurons (VENs) and fork cells within the frontoinsular (FI) and anterior cingulate cortices (ACC) is observed in patients with sporadic behavioral varian...

Полное описание

Библиографические подробности

Главные авторы:	Li-Chun Lin, Alissa L. Nana, Mackenzie Hepker, Ji-Hye Lee Hwang, Stephanie E. Gaus, Salvatore Spina, Celica G. Cosme, Li Gan, Lea T. Grinberg, Daniel H. Geschwind, Giovanni Coppola, Howard J. Rosen, Bruce L. Miller, William W. Seeley
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2019-10-01
Серии:	Acta Neuropathologica Communications
Предметы:	Selective vulnerability Tau MAPT von Economo neurons Anterior cingulate cortex Insula
Online-ссылка:	http://link.springer.com/article/10.1186/s40478-019-0809-0
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!