NSD proteins in anti-tumor immunity and their therapeutic targeting by protein degraders
Abstract Chromatin modifiers, owing to their enzymatic activities and frequent overexpression or hyperactivation in cancer, have emerged as promising therapeutic targets. Among these, the nuclear receptor-binding SET domain (NSD) family of proteins catalyzes lysine methylation—a key histone post-tra...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer
2025-06-01
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| Serier: | Cellular and Molecular Life Sciences |
| Fag: | |
| Online adgang: | https://doi.org/10.1007/s00018-025-05806-6 |
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