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Imipramine-induced immunomodulation and intracellular growth inhibition during Brucella abortus 544 infection in RAW 264.7 cells and BALB/c mice

Brucellosis is a significant zoonotic infection with increasing global prevalence. Traditional treatments rely on antibiotic combinations, but challenges such as drug resistance and relapse necessitate the exploration of alternative therapeutic options. Imipramine hydrochloride (ImiP) has shown pote...

Celý popis

Uloženo v:
Hlavní autoři: Ched Nicole Turbela Aguilar, Tran Xuan Ngoc Huy, Trang Thi Nguyen, Said Abdi Salad, Seong Eun Cho, Il-Hwa Hong, Wongi Min, Hu Jang Lee, Suk Kim
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-06-01
Edice:Frontiers in Veterinary Science
Témata:
Brucella abortus
imipramine hydrochloride
BALB/c mouse
RAW 264.7 cells
immunomodulation
On-line přístup:https://www.frontiersin.org/articles/10.3389/fvets.2025.1598106/full
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