Neutrophils Isolated from Septic Patients Exhibit Elevated Uptake of Vitamin C and Normal Intracellular Concentrations despite a Low Vitamin C Milieu

Vitamin C (ascorbate) plays an important role in neutrophil function and is accumulated by the cells either directly via vitamin C transporters (SVCT) or indirectly following oxidation to dehydroascorbic acid. Septic patients are known to have significantly depleted plasma ascorbate status, but litt...

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Detalhes bibliográficos

Principais autores:	Anitra C. Carr, Stephanie Bozonet, Juliet Pullar, Emma Spencer, Patrice Rosengrave, Geoff Shaw
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-10-01
Colecção:	Antioxidants
Assuntos:	ascorbate vitamin C dehydroascorbic acid sepsis septic shock neutrophils
Acesso em linha:	https://www.mdpi.com/2076-3921/10/10/1607
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