Mitophagy in cisplatin-induced kidney injury: regulatory mechanisms and therapeutic targets

Background Cisplatin is a first-line chemotherapeutic agent widely used in clinical oncology, but its clinical utility is severely limited by cisplatin-induced acute kidney injury (Cis-AKI). Renal tubular epithelial cells (RTECs) are the main target of cisplatin-induced damage, and the pathogenesis...

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Detalhes bibliográficos

Principais autores:	Cheng Yuan, Jinzhou Jiang, Jinxing Ji, Lihua Ni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2026-12-01
coleção:	Annals of Medicine
Assuntos:	Mitophagy cisplatin-induced kidney injury therapeutic targets mtROS PINK1/PARKIN pathway programmed cell death
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/07853890.2026.2672141
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