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Multiple genetic loci define Ca++ utilization by bloodstream malaria parasites

Abstract Background Bloodstream malaria parasites require Ca++ for their development, but the sites and mechanisms of Ca++ utilization are not well understood. We hypothesized that there may be differences in Ca++ uptake or utilization by genetically distinct lines of P. falciparum. These difference...

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Principais autores: Liana Apolis, Joanna Olivas, Prakash Srinivasan, Ambuj K. Kushwaha, Sanjay A. Desai
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-01-01
Serier:BMC Genomics
Fag:
Malaria
Calcium
Antimalarial drug targets
Linkage analysis
EGTA
Plasmodium falciparum
Online adgang:http://link.springer.com/article/10.1186/s12864-018-5418-y
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