Viral escape mutations do not account for non-protection from SIVmac239 challenge in RhCMV/SIV vaccinated rhesus macaques

Simian immunodeficiency virus (SIV) vaccines based upon 68-1 Rhesus Cytomegalovirus (RhCMV) vectors show remarkable protection against pathogenic SIVmac239 challenge. Across multiple independent rhesus macaque (RM) challenge studies, nearly 60% of vaccinated RM show early, complete arrest of SIVmac2...

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Bibliografische gegevens

Hoofdauteurs:	Benjamin N. Bimber, Justine Sunshine, G. W. McElfresh, Jason S. Reed, Reese Pathak, Katherine B. Bateman, Colette M. Hughes, Roxanne M. Gilbride, Julia C. Ford, David Morrow, Jeffrey D. Lifson, Jonah B. Sacha, Scott G. Hansen, Louis J. Picker
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2024-08-01
Reeks:	Frontiers in Immunology
Onderwerpen:	SIV viral escape CMV vaccine vector viral sequence analysis HIV/SIV
Online toegang:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1444621/full
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