TGF-β Induction of miR-143/145 Is Associated to Exercise Response by Influencing Differentiation and Insulin Signaling Molecules in Human Skeletal Muscle

Physical training improves insulin sensitivity and can prevent type 2 diabetes (T2D). However, approximately 20% of individuals lack a beneficial outcome in glycemic control. TGF-β, identified as a possible upstream regulator involved in this low response, is also a potent regulator of microRNAs (mi...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Simon I. Dreher, Selina Höckele, Peter Huypens, Martin Irmler, Christoph Hoffmann, Tim Jeske, Maximilian Hastreiter, Anja Moller, Andreas L. Birkenfeld, Hans-Ulrich Häring, Andreas Peter, Johannes Beckers, Martin Hrabě de Angelis, Cora Weigert
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-12-01
Schriftenreihe:	Cells
Schlagworte:	exercise training response insulin sensitivity TGF-β1 miR-143 miR-145
Online-Zugang:	https://www.mdpi.com/2073-4409/10/12/3443
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