Evaluation of <i>TAB2</i>/<i>SUMO4</i> Region Polymorphisms in Childhood and Adult-Onset Type 1 Diabetes Mellitus in a Southern Brazilian Population

<b>Background/Objective:</b> Type 1 diabetes (T1D) is a complex autoimmune disease characterized by the destruction of insulin-producing pancreatic beta cells. The <i>TAB2/SUMO4</i> locus has been implicated in T1D susceptibility through a biochemical mechanism involving NFκB. Given that alterations...

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Principais autores:	Mateus Santana Lopes, Pedro Henrique Barato Plocharski, Paula Rothbarth Silva, Suzana Nesi-França, Rosângela Roginski Réa, Glaucio Valdameri, Vivian Rotuno Moure, Marcel Henrique Marcondes Sari, Geraldo Picheth, Fabiane Gomes de Moraes Rego
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2026-06-01
Series:	Endocrines
Assuntos:	type 1 diabetes autoimmune diabetes M55V case–control study IDDM5 single nucleotide polymorphism
Acceso en liña:	https://www.mdpi.com/2673-396X/7/2/25
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