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Evaluation of Leptospira interrogans knockdown mutants for LipL32, LipL41, LipL21, and OmpL1 proteins

IntroductionLeptospirosis is a worldwide zoonosis caused by pathogenic and virulent species of the genus Leptospira, whose pathophysiology and virulence factors remain widely unexplored. Recently, the application of CRISPR interference (CRISPRi) has allowed the specific and rapid gene silencing of m...

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Principais autores: Luis G. V. Fernandes, Aline F. Teixeira, Ana L. T. O. Nascimento
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Microbiology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1199660/full
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