Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking‐Dependent and Crosslinking‐Independent Functions

BackgroundThe structural elements of the vascular wall, namely, extracellular matrix and smooth muscle cells (SMCs), contribute to the overall stiffness of the vessel. In this study, we examined the crosslinking‐dependent and crosslinking‐independent roles of tissue transglutaminase (TG2) in vascula...

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Autori principali:	Jochen Steppan, Yehudit Bergman, Kayla Viegas, Dinani Armstrong, Siqi Tan, Huilei Wang, Sean Melucci, Daijiro Hori, Sung Yong Park, Sebastian F. Barreto, Abraham Isak, Sandeep Jandu, Nicholas Flavahan, Mark Butlin, Steven S. An, Alberto Avolio, Dan E. Berkowitz, Marc K. Halushka, Lakshmi Santhanam
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2017-02-01
Serie:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Soggetti:	crosslinking matrix remodeling tissue transglutaminase vascular biology vascular disease vascular smooth muscle
Accesso online:	https://www.ahajournals.org/doi/10.1161/JAHA.116.004161
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