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Induction of aggregation and fusion of cholesterol-containing membrane vesicles by an anti-cholesterol monoclonal antibody

A monoclonal IgM antibody that reacts with cholesterol was able to aggregate small and large unilamellar lipid vesicles. Vesicles aggregated by the antibody could be dispersed by trypsin digestion. Inclusion of unsaturated phosphatidylethanolamine in the vesicle formulation lowered the relative amou...

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Autori principali: Aitziber Agirre, Shlomo Nir, José L. Nieva, Jan Dijkstra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2000-04-01
Serie:Journal of Lipid Research
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Accesso online:http://www.sciencedirect.com/science/article/pii/S002222752032410X
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