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Enhancing conjugation from E. coli to Streptomyces coelicolor by incorporating traJ into mobilizable plasmids

Abstract Streptomyces species are prolific producers of bioactive natural products, yet their genetic manipulation remains constrained by inefficient DNA delivery methods in many strains. Conjugation from methylation-deficient Escherichia coli has become the preferred approach for introducing plasmi...

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Bibliografische gegevens
Hoofdauteurs: Paula Valdés-Chiara, Yago Concha, Sergio Alonso-Fernández, Angel Manteca, Gemma Fernández-García
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer 2025-12-01
Reeks:Applied Microbiology and Biotechnology
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Online toegang:https://doi.org/10.1007/s00253-025-13662-4
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