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A physiologically‐based pharmacokinetic model for tuberculosis drug disposition at extrapulmonary sites

Abstract Tuberculosis (TB) is a leading cause of mortality attributed to an infectious agent. TB primarily targets the lungs, but in about 16% cases can affect other organs as well, giving rise to extrapulmonary TB (EPTB). However, an optimal regimen for EPTB treatment is not defined. Although the r...

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Autori principali: Aparna Ramachandran, Chetan J. Gadgil
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2023-09-01
Serie:CPT: Pharmacometrics & Systems Pharmacology
Accesso online:https://doi.org/10.1002/psp4.13008
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