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A STAT1-Knockout Mouse Model for Chapare Virus Infection and Pathogenesis

Chapare virus (CHAPV) is an <i>Arenaviridae</i> family member and causative agent of Chapare hemorrhagic fever (CHHF). Endemic to Bolivia, CHAPV was found to be the cause of several outbreaks of CHHF in Bolivia in 2003 and 2019 with high case-fatality rates and instances of human-to-human transmissi...

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Principais autores: Stephanie R. Monticelli, Ana I. Kuehne, Thomas G. Batchelor, Joshua B. Richardson, Zebulon Lapoint, Jennifer L. Williams, Susan R. Coyne, Jo Lynne W. Raymond, Xiankun Zeng, Christopher P. Stefan, Jeffrey W. Koehler, Jeffrey R. Kugelman, Andrew S. Herbert
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-03-01
Serier:Viruses
Fag:
Chapare virus
STAT1 knockout
mouse model
arenavirus
Chapare hemorrhagic fever
Online adgang:https://www.mdpi.com/1999-4915/18/3/388
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