5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action

In the effort to identify and develop new HIV-1 inhibitors endowed with innovative mechanisms, we focused our attention on the possibility to target more than one viral encoded enzymatic function with a single molecule. In this respect, we have previously identified by virtual screening a new indoli...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Angela Corona, Rita Meleddu, Olivier Delelis, Frederic Subra, Filippo Cottiglia, Francesca Esposito, Simona Distinto, Elias Maccioni, Enzo Tramontano
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2023-06-01
Reeks:	Frontiers in Cellular and Infection Microbiology
Onderwerpen:	antiviral agents drug design multitarget inhibitors RT inhibitors IN inhibitors
Online toegang:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1193280/full
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!